- Profibus - by PROFIBUS International.
- CIP (Common Industrial Protocol) - Can be treated as application layer common to DeviceNet, CompoNet, ControlNet and EtherNet/IP
- Controller Area Network utilised in many network implementations, including CANopen and DeviceNet
- ControlNet - an implementation of CIP, originally by Allen-Bradley
- DeviceNet - an implementation of CIP, originally by Allen-Bradley
- EtherNet/IP - IP stands for "Industrial Protocol". An implementation of CIP, originally created by Rockwell Automation
- Interbus, Phoenix Contact's protocol for communication over serial links, now part of PROFINET IO
- Modbus RTU or ASCII
- Modbus-NET - Modbus for Networks
- Modbus/TCP
- Host Link, Omron's protocol for communication over serial links.
- Mechatrolink - open protocol originally developed by Yaskawa.
- MelsecNet/10, supported by Mitsubishi Electric.
- Optomux - Serial (RS-422/485) network protocol originally developed by Opto 22 in 1982. The protocol was openly documented and over time used for industrial automation applications.
- SERCOS interface, Open Protocol for hard real-time control of motion and I/O
- SynqNet - Danaher
- PieP - An Open Fieldbus Protocol
- BSAP - Bristol Standard Asynchronous Protocol, developed by Bristol Babcock Inc.